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Validated Luminometric DLR™ Reporter Gene Assay with Thermo Scientific Varioskan® Flash
14 Aug 2008: One of the most common luminometric assays is Dual Luciferase® Reporter Assay from Promega corp. This application note demonstrates the overall efficiency of the Varioskan Flash multitechnology microplate reader in the measurement of this assay. In addition it also includes the performance of the normal DLR assay and results from some tests showing important aspects of the basic behaviour and performance of the DLR™ chemistry. Thermo Fisher Scientific
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Comparison of Flash and Glow ATPAssays with Thermo Scientific Varioskan Flash Luminometry
14 Aug 2008: The ATP reaction catalysed by firefly luciferases is one of the most common luminescent reactions used in research. In this application note, the basic performance of Varioskan Flash microplate luminometer was tested with both glow and flash type ATP assay. Thermo Fisher Scientific
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Optimization of Instrument Settings and Measurement Parameters for Kinetic Fluorometric and Luminometric Assays 14 Aug 2008: The reaction kinetics of fluorometric and luminometric reactions affects the way the measurements must be performed to get the best possible results. This application note demonstrates how the optimization of the instrument settings and measurement parameters can improve the assay sensitivity considerably. Thermo Fisher Scientific
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Roche's xCELLigence System: First Cell Analyzer System Installed at AgenoLab in Stuttgart 13 Aug 2008: On April 3rd, three months before worldwide launch, Roche Applied Science sold the first xCELLigence System at the Analytica 2008 trade in Munich. In July the system has been installed at AgenoLab GmbH & Co. KG in Stuttgart (Germany), a supplier of contract biotechnology and life science laboratory services. Roche Applied Science - a member of the Roche Group
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Putting Past Elucidations to Work for the Future of Antibacterial Research
12 Aug 2008: Sequoia Sciences, Inc., recently purchased and implemented powerful software from ACD/Labs that will allow them to more easily elucidate chemical structures as well as to search and validate completed elucidated structures, effectively eliminating the need to reproduce the results in the future. Advanced Chemistry Development, Inc., (ACD/Labs)
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AnaSpec Introduces New SensoLyte™ 570 Generic MMP Assay Kit with Industry’s Highest Wavelength 08 Aug 2008: Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. The importance of MMPs in tumor development and invasion as well as other diseases is well known. AnaSpec Inc.
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MipTec about to take off by joining forces between Life Sciences Week, ALL-SystemsX.ch-Day, & Jobvector.com 08 Aug 2008: This year, MipTec (October 14-16, 2008) emphasizes the basic science and technology of drug discovery and is being headlined by three leaders in the field: Richard Eglen (PerkinElmer), Mark Fishman (Novartis Pharma AG) & Lee Babiss (F. Hoffmann-La Roche Ltd.). AKM congress Service
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Roche's xCELLigence System Designed to Reduce Animal Testing in Pharmaceutical Development 07 Aug 2008: BOTOX® is an important medicine that over the last 15 years of clinical use has helped millions of patients with serious medical conditions worldwide. Pharmaceutical manufacturers using Clostridium botulinum toxin (BOTOX®) in drugs are required by the Food and Drug Administration (FDA) in the United States and by other worldwide health regulatory agencies to protect patients and consumers by assuring product safety and efficacy. Roche Applied Science - a member of the Roche Group
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Predictor™ hERG Fluorescence Polarization Assay Kit performed on the PHERAstar/PHERAstar Plus
07 Aug 2008: Because of the potentially lethal effects of unintended hERG block, the FDA has recommended that all compounds should be tested for this effect in an electrophysiological (patch-clamp) assay before being tested in humans. This technical note describes the performance of the Predictor™ hERG Assay on BMG LABTECH’s PHERAstar/PHERAstar Plus multifunctional HTS microplate reader. BMG LABTECH
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