Members Approve SBS-ALA Merger 11 May 2010: The leaders of the Society for Biomolecular Sciences (SBS) and the Association for Laboratory Automation (ALA) have been strategizing a merger to unite their scientific societies as one inclusive organization—the Society for Laboratory Automation and Screening (SLAS). As of Wednesday, May 5, both memberships officially authorized the merger with more than 95% of the votes cast in favor. Society for Biomolecular Sciences (SBS)
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Non-Contact Acoustic Liquid Dispensing Systems: New Challenges in Automation and Implementation in the Work Flow 10 May 2010: Agilent Automation Solutions has published a technical poster that describes the integration of true non-contact acoustic liquid dispensing technology within an Agilent BioCel System enabling a new level of high throughput automation in a drug discovery environment. The poster describes the configuration of a fully automated compound management solution for screening and developmental assay plates. Agilent Automation Solutions
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BellBrook Labs Launches Compound Profiling Services with High Content 3D Invasion Assay 06 May 2010: BellBrook Labs announced at the 2010 Society for Biomolecular Screening Symposium the launch of a new invasion assay service for profiling the effects of potential drug molecules on migration of tumor cells through extracellular matrix. The assay was developed as a more physiologically relevant and information-rich alternative to commonly used filter-based assays. BellBrook Labs
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SBS Announces Top Ten Poster Winners at SBS 2010 Conference 04 May 2010: The Society for Biomolecular Sciences (SBS) announces the top ten poster winners of the SBS 2010 Conference and Exhibition. Posters were on display in the exhibit hall at the conference, which took place at the Phoenix Convention Center in Phoenix, Arizona, April 11 – 15. Society for Biomolecular Sciences (SBS)
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Epigenetics Targets –Efficient Hit-Finding Approaches 04 May 2010: In this application note BioFocus use epigenetic targets to identify starting points for lead optimizaton. In order to address a broad range of novel epigenetics targets, rather than screening a full compound collection, BioFocus use computational chemistry workflows which are individually tailored and optimized for selecting the most suited compounds from library subsets for primary screening. These filtered high-throughput screens generate a greatly increased hit-rate. BioFocus
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Are Natural Products Delivering? Experiences and Recommendations from 27 Screening Campaigns 04 May 2010: In this application note from BioFocus, microbial strain subfractions are generated and used in high-throughput screens (HTS) for analysis with regard to diversity, selectivity and strain origin. Natural compounds were identified during the follow up of subfraction screening programs and their chemical properties have been analyzed. Searches in natural product databases revealed that 135 of the 645 identified natural compounds are novel compounds. BioFocus
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Enter Tecan Competition and Win a Party for your Team!
04 May 2010: Send in a photo that captures how important your system is to your team to be in with a chance of winning a huge party for you and 20 of your colleagues. Tecan
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Measurement of Compound-Induced Cytotoxicity with Roche’s xCELLigence Real-Time Cell Analysis System 29 Apr 2010: Monitoring of cell viability and toxicity are critical to many areas of biological and biomedical research. This is true for understanding the molecular and biochemical pathways regulating cell viability, for developing therapeutic agents which modulate cell viability and for identifying potential cytotoxic side effects of potential therapeutic agents. Roche's xCELLigence System has been used for studying cell viability and cell death when testing various cytotoxic compounds. Roche Diagnostics GmbH - a member of the Roche Group
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ChemBridge Presents Fragment Library for Screening
28 Apr 2010: ChemBridge’s Fragment Library is an exemplary collection of small molecules useful for fragment-based screening. The emergence and development of high throughput X-ray crystallography and NMR methodologies for drug discovery have contributed widely to the acceptance and implementation of fragment based screening. The ability to detect low affinity binders has proven invaluable in the introduction and promotion of this aspect of drug discovery and design. ChemBridge Corporation
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Bioo Scientific Launches ELISAs for High-Throughput ApoB Quantitation 26 Apr 2010: Bioo Scientific introduces a new MaxDiscovery™ Apolipoprotein B (ApoB) ELISA Kit, a complete, two-step ELISA that analyzes the quantity of ApoB in tissues, serum, plasma or cultured cells for research purposes. This kit offers precise protein measurement along with the ability to analyze multiple samples in low-volume, high-throughput experiments. Bioo Scientific
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